CALL FOR PAPERS Bioengineering the Lung: Molecules, Materials, Matrix, Morphology, and Mechanics Differential deposition of fibronectin by asthmatic bronchial epithelial cells
نویسندگان
چکیده
Qi Ge, Qingxiang Zeng, Gavin Tjin, Edmund Lau, Judith L. Black, Brian G. G. Oliver,* and Janette K. Burgess* Respiratory Cellular and Molecular Biology Group, Woolcock Institute of Medical Research, Sydney, New South Wales, Australia; Discipline of Pharmacology, Sydney Medical School, The University of Sydney, New South Wales, Australia; and Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
منابع مشابه
Differential deposition of fibronectin by asthmatic bronchial epithelial cells.
Altered ECM protein deposition is a feature in asthmatic airways. Fibronectin (Fn), an ECM protein produced by human bronchial epithelial cells (HBECs), is increased in asthmatic airways. This study investigated the regulation of Fn production in asthmatic or nonasthmatic HBECs and whether Fn modulated HBEC proliferation and inflammatory mediator secretion. The signaling pathways underlying tra...
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